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LIFENOX: No advantage of VTE prophylaxis in hospitalized medical service patients

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The surprising results of the LIFENOX trial—which failed to show an advantage of daily enoxaparin vs placebo to reduce mortality in the acute-care setting—challenge dogma. What explains these results?

See also:

Kakkar AK, Cimminiello C, Goldhaber SZ, et al. Low-molecular-weight heparin and mortality in acutely ill medical patients. N Engl J Med 2012; 365:2463-2472. Abstract.

Enoxaparin prophylaxis doesn't cut mortality in acute-care setting

Comments

How many additional research studies will be conducted to further investigate VTE prophylaxis benefits for specific populations?  Additionally, how will this affect the AHA's evidence-based measure?

 Thank you...


Posted by Maggie, Jan 23, 2012 at 09:54 AM, EDT

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